Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrEConserved hypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (396 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase catalytic subunit.
 
 
 0.998
BAJ50429.1
Orotidine-5'-phosphate decarboxylase.
 
 0.998
BAJ50873.1
Oxidoreductase FAD/NAD(P)-binding subunit.
 
  
 0.834
BAJ50923.1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
    
  0.805
BAJ50605.1
Hydroxymethylpyrimidine transporter.
   
    0.741
BAJ51367.1
tRNA and rRNA cytosine-C5-methylases.
      0.696
BAJ51013.1
Multiple antibiotic resistance protein.
       0.693
BAJ50430.1
1-pyrroline-5-carboxylate dehydrogenase.
       0.682
BAJ50426.1
Conserved hypothetical protein; Peptidase dimerisation domain.
  
    0.613
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
  
 0.608
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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