Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ50589.1Conserved hypothetical protein; Methyltransferase domain. (170 aa)    
Predicted Functional Partners:
rps5
Small subunit ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.720
BAJ49902.1
Hypothetical protein.
  
 0.632
BAJ51360.1
NADH dehydrogenase I subunit B; Belongs to the complex I 20 kDa subunit family.
    
 0.622
BAJ51362.1
NADH dehydrogenase I subunit D; Belongs to the complex I 49 kDa subunit family.
    
 0.585
BAJ50590.1
Conserved hypothetical protein; Nucleotidyltransferase domain.
       0.584
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.578
guaB
Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
   0.571
BAJ51361.1
NADH dehydrogenase I subunit C.
   
 0.562
BAJ50115.1
Small subunit ribosomal protein S26e.
 
  0.561
BAJ50593.1
Adenylosuccinate lyase.
  
  
 0.561
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.