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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
CSUB_C08123-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; C-terminus of hypothetical conserved protein. (214 aa)    
Predicted Functional Partners:
BAJ50465.1
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit.
 0.999
BAJ51126.1
3-isopropylmalate dehydrogenase.
 
 
 0.994
BAJ50674.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.981
BAJ50888.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.976
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.965
BAJ50621.1
Isocitrate dehydrogenase.
 
  
 0.932
BAJ50111.1
Carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.908
BAJ51399.1
2-isopropylmalate synthase.
 
 
 0.907
BAJ50673.1
Acetolactate synthase I/II/III large subunit.
  
  
 0.879
BAJ51056.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.844
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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