Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50674.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (507 aa)    
Predicted Functional Partners:
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 0.996
BAJ50465.1
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit.
 
 0.989
BAJ50673.1
Acetolactate synthase I/II/III large subunit.
  
 
 0.983
CSUB_C0812
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; C-terminus of hypothetical conserved protein.
 
 
 0.981
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.952
BAJ50234.1
acetyl-CoA C-acyltransferase.
  
 
 0.932
BAJ51204.1
acetyl-CoA C-acetyltransferase; propanoyl-CoA C-acyltransferase (EC:2.3.1.176).
  
 
 0.932
BAJ51205.1
acetyl-CoA C-acetyltransferase.
  
 
 0.932
BAJ51321.1
acetyl-CoA C-acetyltransferase.
  
 
 0.932
BAJ51389.1
acetyl-CoA synthetase.
  
 
 0.923
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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