Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50708.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (258 aa)    
Predicted Functional Partners:
BAJ51440.1
Dihydrolipoamide dehydrogenase.
 0.989
BAJ50651.1
Pyruvate dehydrogenase E1 component subunit beta.
 0.975
BAJ50835.1
Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.962
BAJ51441.1
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 0.950
BAJ50112.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.910
BAJ51201.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.907
BAJ50221.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.906
BAJ50652.1
Pyruvate dehydrogenase E1 component subunit alpha.
  
 0.891
BAJ50923.1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.842
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.831
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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