Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BAJ50761.1Conserved hypothetical protein; GHMP kinases N terminal domain. (306 aa)    
Predicted Functional Partners:
BAJ50760.1
Conserved hypothetical protein.
       0.860
htpX
Peptidase M48; Heat shock protein HtpX; Belongs to the peptidase M48B family.
  
    0.850
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.801
BAJ51056.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
  
    0.742
BAJ50320.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
    0.701
BAJ50821.1
Hypothetical protein; Similar to N-terminal of 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
    0.701
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
       0.700
BAJ50212.1
Methanol dehydrogenase regulator.
   
    0.686
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.674
BAJ50321.1
Methylcobalamin:homocysteine methyltransferase.
 
    0.668
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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