Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BAJ50821.1Hypothetical protein; Similar to N-terminal of 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (128 aa)    
Predicted Functional Partners:
BAJ50822.1
Hypothetical protein; Similar to C-terminal of OsmC family protein.
       0.791
BAJ50761.1
Conserved hypothetical protein; GHMP kinases N terminal domain.
  
    0.701
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 0.694
BAJ50320.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
     0.581
BAJ51094.1
Aspartate kinase; Belongs to the aspartokinase family.
  
  
 0.495
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.494
BAJ51479.1
Serine hydroxymethyltransferase.
  
  
 0.494
BAJ50823.1
HEPN domain-containing protein.
 
     0.487
BAJ51032.1
Homoserine dehydrogenase.
  
  
 0.484
BAJ50114.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.481
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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