Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (130 aa)    
Predicted Functional Partners:
rps12
Small subunit ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 
 0.989
BAJ50180.1
Large subunit ribosomal protein L13.
 
 
 0.989
rps6e
Small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.988
rps3ae
Small subunit ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.988
rpl18
Large subunit ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.988
BAJ50184.1
Small subunit ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.987
rps17
Small subunit ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.987
rps7
Small subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.987
rps13
Small subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
 
 
 0.986
rps19p
Small subunit ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
 
 0.985
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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