Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
BAJ50625.1
Succinate dehydrogenase iron-sulfur protein.
 
 0.987
BAJ50622.1
Succinate dehydrogenase flavoprotein subunit.
 
 0.986
BAJ50623.1
Succinate dehydrogenase cytochrome b-556 subunit.
  
 
 0.979
BAJ50624.1
Succinate dehydrogenase subunit.
  
 
 0.943
BAJ51114.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.943
BAJ51485.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.927
BAJ50994.1
Isocitrate lyase.
   
 
 0.919
BAJ51486.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.918
BAJ50895.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.872
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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