Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ51016.1Translation initiation factor eIF-2B; Belongs to the eIF-2B alpha/beta/delta subunits family. (279 aa)    
Predicted Functional Partners:
BAJ51403.1
Translation initiation factor eIF-2 alpha subunit.
   
 0.971
BAJ49972.1
Elongation factor EF-1 alpha subunit.
   
 0.900
BAJ50293.1
Translation initiation factor eIF-2 gamma subunit.
   
 0.900
BAJ50495.1
Nucleotidyl transferase.
   
 0.825
BAJ51077.1
Nucleotidyl transferase.
   
 0.825
BAJ51343.1
Conserved hypothetical protein.
   
 0.825
BAJ51350.1
Bifunctional protein GlmU.
   
 0.825
BAJ51017.1
Alcohol dehydrogenase.
       0.773
BAJ51018.1
Amidohydrolase.
       0.773
nfo
Deoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.762
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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