Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (310 aa)    
Predicted Functional Partners:
BAJ50674.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.996
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.993
BAJ50888.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.985
BAJ49970.1
Threonine dehydratase.
  
 0.947
BAJ50111.1
Carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.946
BAJ51032.1
Homoserine dehydrogenase.
  
 
 0.925
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.898
BAJ50598.1
Pyruvate ferredoxin oxidoreductase, gamma subunit.
    
 0.855
BAJ49933.1
Pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.839
BAJ50600.1
Pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.839
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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