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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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[Homology]
Score
BAJ51114.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (378 aa)    
Predicted Functional Partners:
BAJ51440.1
Dihydrolipoamide dehydrogenase.
 0.997
BAJ51441.1
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 0.995
BAJ50112.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.985
BAJ51201.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.984
BAJ50745.1
Citrate synthase.
  
 0.978
BAJ51498.1
Citrate synthase.
  
 0.978
BAJ50651.1
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.976
BAJ50835.1
Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.968
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.965
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.943
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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