Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BAJ51121.1Metallophosphoesterase. (261 aa)    
Predicted Functional Partners:
BAJ51257.1
Lhr and Lhr-like helicase [EC:3.6.1.-].
 
    0.873
BAJ51122.1
Conserved hypothetical protein.
       0.860
BAJ51281.1
Hypothetical protein.
     
 0.860
top6A
DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.778
BAJ51119.1
Multicomponent Na+:H+ antiporter subunit D.
       0.668
BAJ50516.1
Hypothetical protein.
 
     0.612
nusA
N utilization substance protein A; Participates in transcription termination. Belongs to the NusA family.
  
     0.556
BAJ51118.1
Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.551
BAJ50587.1
Archaeal cell division control protein 6; Involved in regulation of DNA replication.
  
     0.547
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.544
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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