Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa)    
Predicted Functional Partners:
BAJ51032.1
Homoserine dehydrogenase.
 
 0.996
BAJ49911.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.980
BAJ50915.1
Threonine synthase.
  
 
 0.980
BAJ51006.1
Threonine synthase.
  
 
 0.980
BAJ51571.1
Threonine synthase.
  
 
 0.980
BAJ51094.1
Aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.961
BAJ51126.1
3-isopropylmalate dehydrogenase.
 
  
 0.907
BAJ50751.1
Aspartate-semialdehyde dehydrogenase.
 
  
 0.904
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.898
BAJ50320.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
 
 
 0.862
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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