Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ51144.1Conserved hypothetical protein; Beta-lactamase domain-containing protein. (467 aa)    
Predicted Functional Partners:
BAJ50447.1
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.767
BAJ51516.1
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.767
rpl37ae
Large subunit ribosomal protein L37Ae; Binds to the 23S rRNA.
   
    0.629
BAJ50143.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
   
 0.572
BAJ51143.1
Fe-S cluster assembly ATP-binding protein SufC.
       0.569
BAJ50229.1
Phosphomannomutase; Belongs to the phosphohexose mutase family.
 
  
 0.555
rpl23
Large subunit ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
  
 0.523
rps15
Small subunit ribosomal protein S15.
  
  
 0.511
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
  
 0.502
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
  
 0.496
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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