Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (319 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
 
 0.961
BAJ51342.1
Phosphomethylpyrimidine kinase.
     
 0.916
BAJ50144.1
Nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
     
  0.900
adkA
Adenylate kinase; Belongs to the archaeal adenylate kinase family.
     
  0.900
BAJ51183.1
Heat shock protein DnaJ-like.
  
  
 0.835
BAJ51182.1
Dolichol-phosphate mannosyltransferase.
       0.779
BAJ51185.1
Conserved hypothetical protein.
       0.737
BAJ51367.1
tRNA and rRNA cytosine-C5-methylases.
  
    0.710
BAJ51184.1
Thioesterase superfamily protein.
       0.709
BAJ51186.1
Thiolase.
     
 0.709
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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