Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ51201.1Pyruvate dehydrogenase E1 component subunit alpha. (347 aa)    
Predicted Functional Partners:
BAJ51441.1
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 0.999
BAJ50651.1
Pyruvate dehydrogenase E1 component subunit beta.
 0.995
BAJ51114.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.984
BAJ51440.1
Dihydrolipoamide dehydrogenase.
 
 
 0.966
BAJ50662.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.915
BAJ51486.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.915
BAJ51056.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.914
BAJ51485.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
 0.909
BAJ50708.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.907
BAJ50112.1
Pyruvate dehydrogenase E1 component subunit alpha.
  
  
 
0.903
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
Server load: low (38%) [HD]