Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ51281.1Hypothetical protein. (511 aa)    
Predicted Functional Partners:
BAJ51472.1
Replication factor A1.
  
 
 0.968
BAJ51121.1
Metallophosphoesterase.
     
 0.860
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
    
   0.785
BAJ50152.1
Segregation and condensation protein B.
       0.700
BAJ50366.1
Translation initiation factor eIF-2 beta subunit.
       0.700
BAJ50367.1
Conserved hypothetical protein.
       0.678
BAJ51282.1
Electron transfer flavoprotein beta subunit.
       0.655
BAJ51283.1
Electron transfer flavoprotein alpha subunit.
       0.655
BAJ51284.1
Electron transfer flavoprotein-quinone oxidoreductase.
       0.655
BAJ51280.1
Hypothetical protein.
       0.572
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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