Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ51440.1Dihydrolipoamide dehydrogenase. (459 aa)    
Predicted Functional Partners:
BAJ51441.1
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 
 0.998
BAJ51114.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.997
BAJ50708.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.989
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.978
BAJ50651.1
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.971
BAJ50112.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 
 0.966
BAJ51201.1
Pyruvate dehydrogenase E1 component subunit alpha.
 
 
 0.966
BAJ51279.1
Glycine cleavage system aminomethyltransferase.
  
 0.966
gcvPB
Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
  
 0.949
BAJ51277.1
Glycine dehydrogenase subunit 1.
  
 
 0.932
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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