Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ51532.16-pyruvoyl tetrahydrobiopterin synthase. (156 aa)    
Predicted Functional Partners:
BAJ51533.1
Transcription regulator ExsB related protein.
 
  
 0.993
BAJ51531.1
Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.806
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.744
BAJ51535.1
Conserved hypothetical protein.
 
     0.714
BAJ51492.1
Valyl tRNA-synthetase.
       0.700
cysS
cysteinyl-tRNA synthetase.
  
  
 0.683
tgtA
Queuine tRNA-ribosyltransferas; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
 
 
 0.638
BAJ50763.1
Conserved hypothetical protein; GTP cyclohydrolase.
     
 0.593
BAJ50006.1
threonyl-tRNA synthetase.
   
 
 0.538
BAJ50914.1
Conserved hypothetical protein.
 
     0.523
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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