Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adeAdenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (596 aa)    
Predicted Functional Partners:
BAJ50420.1
Phosphoribosyl transferase domain protein.
    
 0.921
BAJ51561.1
Simple sugar ABC transporter substrate-binding protein.
       0.688
BAJ51564.1
Conserved hypothetical protein; Amidohydrolase.
     
 0.639
BAJ50105.1
Adenine phosphoribosyltransferase; Phosphoribosyl transferase domain.
    
 0.607
BAJ50279.1
Adenine phosphoribosyltransferase, fused to N-terminal DNA-binding.
    
 0.607
BAJ51559.1
Simple sugar transporter permease.
       0.590
BAJ51558.1
Simple sugar ABC transporter permease.
       0.587
BAJ51560.1
Simple sugar transporter ATP-binding protein.
       0.584
ppcA
Phosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
       0.559
BAJ51563.1
F420-dependent N5,N10-methenyltetrahydromethanopterin reductase.
       0.555
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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