STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I7M1D3_TETTSSerine/Threonine kinase domain protein. (571 aa)    
Predicted Functional Partners:
Q23JA1_TETTS
BRCA1 carboxy-terminus (BRCT) domain protein.
   
 0.632
I7M1J1_TETTS
Protein kinase.
   
 
 0.543
Q24FA9_TETTS
Phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.539
HHF1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.527
I7M6Z4_TETTS
DNA helicase; Belongs to the MCM family.
   
 
 0.521
Q233C0_TETTS
BRCA1 carboxy-terminus (BRCT) domain protein.
   
 0.516
Q240P5_TETTS
ERCC4 domain protein.
   
 
 0.502
I7M048_TETTS
Histone chaperone asf1.
   
 
 0.497
I7M1V7_TETTS
DNA helicase; Belongs to the MCM family.
   
 
 0.483
Q23YR0_TETTS
MCM2/3/5 family protein.
   
 
 0.483
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.