STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I7M1M8_TETTSEndonuclease/exonuclease/phosphatase family protein. (371 aa)    
Predicted Functional Partners:
I7MJ06_TETTS
Origin recognition complex subunit 2.
      
 0.688
I7M645_TETTS
Tyrosyl-DNA phosphodiesterase family protein.
   
  
 0.620
I7MLY5_TETTS
Tyrosyl-DNA phosphodiesterase family protein.
   
  
 0.620
Q23RV6_TETTS
Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.
   
  
 0.589
I7MFS9_TETTS
Small ubiquitin-related modifier.
   
 
 0.566
Q24BB2_TETTS
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
      
 0.499
A4VEG9_TETTS
ATP-dependent DNA helicase II, 70 kDa subunit (Ku70).
     
 0.454
I7MAM7_TETTS
ATP-dependent DNA helicase II 70 kDa subunit.
     
 0.454
I7LWU7_TETTS
Ku70/Ku80 beta-barrel domain protein.
     
 0.443
A4VDK0_TETTS
Ubiquitin.
   
   0.432
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.