STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I7M6M4_TETTSE3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1587 aa)    
Predicted Functional Partners:
I7LX15_TETTS
Hect domain and RCC1-like domain protein.
   
 0.482
I7LXX9_TETTS
Chromosome condensation regulator RCC1 repeat protein.
   
 0.482
I7M3P8_TETTS
Ubiquitin-conjugating enzyme.
    
 
 0.472
I7MI37_TETTS
Ubiquitin-conjugating enzyme.
    
 
 0.472
Q22UQ2_TETTS
Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.472
Q238T8_TETTS
Ubiquitin-conjugating enzyme.
    
 
 0.472
I7M8Y2_TETTS
RING Zn-finger protein, putative.
   
 0.460
I7MAZ2_TETTS
Ubiquitin family protein.
   
 0.425
I7MMJ4_TETTS
Ubiquitin-40S ribosomal protein S27a.
   
 0.425
Q22L31_TETTS
Uncharacterized protein.
   
 0.425
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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