I7M7R4_TETTS protein (Tetrahymena thermophila)

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I7M7R4_TETTS

Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (1056 aa)

Predicted Functional Partners:

Q234F3_TETTS

0.998

Q23DV6_TETTS

0.997

I7M9Y2_TETTS

0.982

I7MFR5_TETTS

0.981

Q23K14_TETTS

0.979

Q23W20_TETTS

0.979

I7MKD2_TETTS

0.974

I7LZY0_TETTS

0.959

I7LTY1_TETTS

0.953

Q23VX7_TETTS

0.936

Your Current Organism:

Tetrahymena thermophila

NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I7LTY1_TETTS	I7LZY0_TETTS	I7LTY1	I7LZY0	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.990
I7LTY1_TETTS	I7M7R4_TETTS	I7LTY1	I7M7R4	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.	0.953
I7LTY1_TETTS	I7M9Y2_TETTS	I7LTY1	I7M9Y2	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxo acid dehydrogenase acyltransferase domain protein.	0.930
I7LTY1_TETTS	I7MFR5_TETTS	I7LTY1	I7MFR5	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	NAD-dependent isocitrate dehydrogenase.	0.728
I7LTY1_TETTS	I7MKD2_TETTS	I7LTY1	I7MKD2	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	NAD-dependent isocitrate dehydrogenase.	0.786
I7LTY1_TETTS	Q234F3_TETTS	I7LTY1	Q234F3	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoglutarate dehydrogenase complex protein, putative.	0.993
I7LTY1_TETTS	Q23DV6_TETTS	I7LTY1	Q23DV6	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Dihydrolipoyl dehydrogenase.	0.874
I7LTY1_TETTS	Q23K14_TETTS	I7LTY1	Q23K14	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.848
I7LTY1_TETTS	Q23VX7_TETTS	I7LTY1	Q23VX7	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.907
I7LTY1_TETTS	Q23W20_TETTS	I7LTY1	Q23W20	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.848
I7LZY0_TETTS	I7LTY1_TETTS	I7LZY0	I7LTY1	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.990
I7LZY0_TETTS	I7M7R4_TETTS	I7LZY0	I7M7R4	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.	0.959
I7LZY0_TETTS	I7M9Y2_TETTS	I7LZY0	I7M9Y2	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxo acid dehydrogenase acyltransferase domain protein.	0.940
I7LZY0_TETTS	I7MFR5_TETTS	I7LZY0	I7MFR5	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	NAD-dependent isocitrate dehydrogenase.	0.816
I7LZY0_TETTS	I7MKD2_TETTS	I7LZY0	I7MKD2	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	NAD-dependent isocitrate dehydrogenase.	0.741
I7LZY0_TETTS	Q234F3_TETTS	I7LZY0	Q234F3	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoglutarate dehydrogenase complex protein, putative.	0.947
I7LZY0_TETTS	Q23DV6_TETTS	I7LZY0	Q23DV6	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoyl dehydrogenase.	0.999
I7LZY0_TETTS	Q23K14_TETTS	I7LZY0	Q23K14	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.683
I7LZY0_TETTS	Q23VX7_TETTS	I7LZY0	Q23VX7	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.768
I7LZY0_TETTS	Q23W20_TETTS	I7LZY0	Q23W20	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.683