STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I7MH68_TETTSArp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (342 aa)    
Predicted Functional Partners:
I7LTL3_TETTS
Actin; Belongs to the actin family.
   
 0.999
I7LUJ4_TETTS
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.999
I7LW62_TETTS
Actin.
   
 0.999
Q22Y88_TETTS
Actin-related protein 2/3 complex subunit 1A/1B.
   
 0.999
Q23YX7_TETTS
ARP2/3 complex 20 kDa subunit (ARPC4).
   
 0.999
Q22NU2_TETTS
WH1 domain protein.
    
 0.993
Q239Z3_TETTS
DUF2013 domain-containing protein.
   
 0.993
I7M0B6_TETTS
WD domain, G-beta repeat protein.
   
   0.822
Q22RI7_TETTS
WD40 domain protein.
   
   0.822
I7MJK5_TETTS
Beta-Pak interactive eXchange factor Src-like 3 domain protein.
   
 
 0.813
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.