STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q22CB9_TETTSSphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family. (600 aa)    
Predicted Functional Partners:
Q22DI5_TETTS
LAG1 longevity assurance protein.
     
 0.908
I7M480_TETTS
Fatty acid desaturase.
     
 0.906
I7MJW3_TETTS
Fatty acid desaturase.
     
 0.906
Q22AK2_TETTS
N-acylethanolamine-hydrolyzing acid amidase.
    
 0.665
Q22Y46_TETTS
Linear amide C-N hydrolase, choloylglycine hydrolase family protein.
    
 0.665
Q24DP9_TETTS
Linear amide C-N hydrolase, choloylglycine hydrolase family protein.
    
 0.665
Q23R98_TETTS
Linear amide C-N hydrolase, choloylglycine hydrolase family protein.
     
  0.650
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.