STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q24FV9_TETTS3'-5' exonuclease. (584 aa)    
Predicted Functional Partners:
I7M048_TETTS
Histone chaperone asf1.
   
    0.694
Q237U0_TETTS
Pyridine nucleotide-disulfide oxidoreductase.
   
    0.691
I7MCW7_TETTS
U3 small nucleolar RNA-associated protein, putative.
   
    0.690
Q24BX8_TETTS
Structural maintenance of chromosomes protein.
   
    0.688
A4VDG6_TETTS
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.613
I7MMQ1_TETTS
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.613
I7MGX3_TETTS
Nucleolar protein 5a.
   
    0.600
I7LY08_TETTS
Gtr1/RagA G motif protein.
   
    0.459
HEN1
Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Required for programmed DNA elimination; Belongs to the methyltransferase superfamily. HEN1 family.
      
 0.422
I7ML23_TETTS
Metal-dependent phosphohydrolase.
   
    0.412
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.