STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (337 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.975
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.975
lspA
Putative lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.846
EAR24398.1
COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
    0.813
lnt
Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
 
   
 0.794
EAR26159.1
Putative inner membrane protein translocase component YidC; COG0706 Preprotein translocase subunit YidC.
  
  
 0.693
EAR26158.1
COG1847 Predicted RNA-binding protein.
 
    0.683
EAR24399.1
Mambrane protein.
       0.659
EAR24394.1
Glutamate synthase, alpha subunit; COG0067 Glutamate synthase domain 1.
       0.633
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
     0.625
Your Current Organism:
actinobacterium PHSC20C1
NCBI taxonomy Id: 312284
Other names: m. actinobacterium PHSC20C1, marine actinobacterium PHSC20C1, marine actinobacterium str. PHSC20C1, marine actinobacterium strain PHSC20C1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.