STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR25702.1Formimidoylglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. (285 aa)    
Predicted Functional Partners:
hutI
Putative chlorohydrolase; COG1228 Imidazolonepropionase and related amidohydrolases.
 
 
 0.992
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.914
hutH
COG2986 Histidine ammonia-lyase.
 
  
 0.903
EAR26235.1
COG0506 Proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.867
EAR24583.1
COG0076 Glutamate decarboxylase and related PLP-dependent proteins.
  
  
  0.854
argG
COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.835
purQ
Phosphoribosyl formylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
    
  0.833
EAR25705.1
Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator.
 
   
 0.635
EAR25900.1
COG2986 Histidine ammonia-lyase.
  
  
 0.526
EAR25147.1
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 
  0.473
Your Current Organism:
actinobacterium PHSC20C1
NCBI taxonomy Id: 312284
Other names: m. actinobacterium PHSC20C1, marine actinobacterium PHSC20C1, marine actinobacterium str. PHSC20C1, marine actinobacterium strain PHSC20C1
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