node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fhs | guaA | VF_1793 | VF_0638 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.731 |
fhs | purC | VF_1793 | VF_1498 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.856 |
fhs | purD | VF_1793 | VF_2395 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.673 |
fhs | purE | VF_1793 | VF_2537 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.645 |
fhs | purF | VF_1793 | VF_1691 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.785 |
fhs | purK | VF_1793 | VF_2538 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.464 |
fhs | purL | VF_1793 | VF_0652 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.973 |
fhs | purM | VF_1793 | VF_1928 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole synthetase. | 0.446 |
fhs | purN | VF_1793 | VF_1929 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.966 |
fhs | purT | VF_1793 | VF_1487 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.900 |
guaA | fhs | VF_0638 | VF_1793 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.731 |
guaA | purC | VF_0638 | VF_1498 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.679 |
guaA | purD | VF_0638 | VF_2395 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.909 |
guaA | purE | VF_0638 | VF_2537 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.585 |
guaA | purF | VF_0638 | VF_1691 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.890 |
guaA | purK | VF_0638 | VF_2538 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.712 |
guaA | purL | VF_0638 | VF_0652 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.982 |
guaA | purM | VF_0638 | VF_1928 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole synthetase. | 0.611 |
guaA | purN | VF_0638 | VF_1929 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.486 |
purC | fhs | VF_1498 | VF_1793 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.856 |