STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxOAutoinducer repressor protein LuxO. (476 aa)    
Predicted Functional Partners:
luxU
Autoinducer phosphorelay protein LuxU.
  
 
 0.996
rpoN
RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.936
sypG
Sigma-54 dependent transcriptional regulator; Syp polysaccharide locus.
  
  
0.907
luxQ
Membrane-bound sensor histidine kinase LuxQ.
 
 
 0.868
luxS
S-ribosylhomocysteinase, autoinducer-2 synthase protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.821
luxP
Periplasmic AI-2 binding protein LuxP.
      
 0.821
ainR
Putative autoinducer regulatory protein AinR.
 
 
 0.817
litR
Quorum sensing transcriptional regulator LitR (HapR).
      
 0.770
hfq
RNA chaperone Hfq (HF-I); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
     
 0.734
ainS
C8-HSL autoinducer synthesis protein AinS.
      
 0.714
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.