STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gadAGlutamate decarboxylase A, PLP-dependent; Catalyzes the pyridoxal-dependent decarboxylation of glutamate to produce 4-aminobutanoate. Has weak activity with aspartate, but cannot complement an E. coli panD deletion mutant. Belongs to the group II decarboxylase family. (464 aa)    
Predicted Functional Partners:
yneH
Predicted glutaminase; Belongs to the glutaminase family.
  
 
 0.937
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.936
gltB
Glutamate synthase, large subunit.
    
 0.924
ggt
Gamma-glutamyltranspeptidase.
     
 0.914
glnA
Glutamine synthetase.
    
 0.908
VF_1284
NAD-specific glutamate dehydrogenase.
     
 0.906
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.905
panP
Glutamate decarboxylase; Catalyzes the pyridoxal-dependent decarboxylation of aspartate to produce beta-alanine. Has weak activity with glutamate. Belongs to the group II decarboxylase family.
     
  0.900
gltD
Glutamate synthase, 4Fe-4S protein, small subunit.
     
  0.900
purA-2
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.856
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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