STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtKMultidrug efflux system transporter; Multidrug efflux pump that functions as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (460 aa)    
Predicted Functional Partners:
dinF
DNA-damage-inducible SOS response protein.
      
 0.814
fieF
Zinc transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
  
 0.700
gapA
Glyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.682
zntA
Zinc, cobalt and lead efflux system ATPase.
   
  
 0.639
queC
Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
   
 0.614
mutT
Nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP; Belongs to the Nudix hydrolase family.
  
  
 0.582
mutY
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
 
  
 0.537
ribC
Riboflavin synthase, alpha subunit.
  
    0.530
lexA
DNA-binding transcriptional repressor of SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.499
metB
Cystathionine gamma-synthase, PLP-dependent.
  
  
 0.461
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.