STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppAProtease IV (signal peptide peptidase). (618 aa)    
Predicted Functional Partners:
VF_A0008
Phospholipase.
      
 0.753
fadH
2,4-dienoyl-CoA reductase, NADH and FMN-linked.
       0.696
acfD
Accessory colonization factor AcfD-like protein, predicted inner membrane lipoprotein.
      
 0.680
ansA
Cytoplasmic L-asparaginase I.
       0.594
VF_1915
D-alanyl-D-alanine carboxypeptidase.
      
 0.556
luxP
Periplasmic AI-2 binding protein LuxP.
      
 0.493
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
     
 0.485
VF_1598
Exochitinase.
      
 0.478
toxS
Regulatory protein ToxS.
      
 0.474
ompT
Omptin family protease OmpT.
      
 0.474
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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