STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfiDPyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins. (125 aa)    
Predicted Functional Partners:
adhE
Fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.863
pflB
Pyruvate formate lyase I.
    
   0.837
VF_A0142
Formate acetyltransferase; Putative transporter, NadC family protein, -1 frameshift to create pseudogene.
    
   0.837
pflA
Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
     0.774
yjjW
Predicted pyruvate formate lyase activating enzyme.
  
     0.761
dmsA
Dimethyl sulfoxide reductase, anaerobic, subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.672
hutC
Histidine utilization repressor.
      
 0.672
nfo
Endonuclease IV with intrinsic 3'-5' exonuclease activity.
       0.620
fis
Global DNA-binding transcriptional dual regulator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
      
 0.590
ung
uracil-DNA-glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
       0.566
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.