STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnKNitrogen regulatory protein GlnK; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
amtB
Ammonium transporter.
 
 0.999
ntrB
Nitrogen regulatory sensory histidine kinase in two-component regulatory system with NtrC.
  
 
 0.857
glnA
Glutamine synthetase.
 
 
 0.812
glnD
Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 
 0.810
gltB
Glutamate synthase, large subunit.
     
 0.759
argA
Fused acetylglutamate kinase-like (inactive)/amino acid N-acetyltransferase.
   
 
 0.686
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.676
VF_2151
iron(III) ABC transporter, periplasmic binding protein.
       0.675
hvnA
Halovibrin HvnA.
     
 0.669
VF_A0319
Hydroxymethylpyrimidine-binding protein.
   
 
 0.546
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
Server load: low (18%) [HD]