STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase, decarboxylase component E1, thiamin-binding; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)    
Predicted Functional Partners:
aceF
Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
lpd
Lipoamide dehydrogenase, E3 component is part of three enzyme complexes.
 
 
 0.987
VF_2301
Dihydrolipoamide dehydrogenase.
  
 
 0.946
oadA
Oxaloacetate decarboxylase alpha subunit.
  
 
 0.937
VF_1242
Phosphoenolpyruvate synthase.
     
 0.919
pykF
Pyruvate kinase I; Belongs to the pyruvate kinase family.
  
 
 0.918
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 
 0.918
maeA
Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Belongs to the malic enzymes family.
    
 0.916
maeB
Fused malic enzyme predicted oxidoreductase/predicted phosphotransacetylase.
    
 0.916
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
   
 
 0.909
Your Current Organism:
Aliivibrio fischeri
NCBI taxonomy Id: 312309
Other names: A. fischeri ES114, Aliivibrio fischeri ES114, Vibrio fischeri ES114, Vibrio fischeri str. ES114, Vibrio fischeri strain ES114
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.