STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cre-sams-1S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (330 aa)    
Predicted Functional Partners:
CRE_11691
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.991
CRE_17193
Hcy-binding domain-containing protein.
  
 
 0.973
Cre-smd-1
S-adenosylmethionine decarboxylase proenzyme.
   
 
 0.972
Cre-tatn-1
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
  
 0.969
CRE_28757
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 
0.937
CRE_28655
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 
0.937
CRE_04131
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.905
CRE_24540
PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.
  
 
 0.896
CRE_13876
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.886
Cre-ahcy-1
Adenosylhomocysteinase.
  
 
 0.872
Your Current Organism:
Caenorhabditis remanei
NCBI taxonomy Id: 31234
Other names: C. remanei, Caenorhabditis vulgaris
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