SMTD_LOCUS210 protein (Schistosoma mattheei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SMTD_LOCUS210

MCM domain-containing protein; Belongs to the MCM family. (467 aa)

Predicted Functional Partners:

MCM7

0.998

SMTD_LOCUS5919

0.995

A0A183PD61

0.995

SMTD_LOCUS3062

0.994

SMTD_LOCUS7887

0.994

A0A183PB98

0.992

A0A183PK31

0.992

A0A183PWM5

0.992

SMTD_LOCUS9260

0.990

A0A183PWI4

0.989

Your Current Organism:

Schistosoma mattheei

NCBI taxonomy Id: 31246
Other names: S. mattheei

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A183PB98	A0A183PD61	A0A183PB98	A0A183PD61	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.996
A0A183PB98	A0A183PK31	A0A183PB98	A0A183PK31	MCM domain-containing protein; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.998
A0A183PB98	A0A183PWI4	A0A183PB98	A0A183PWI4	MCM domain-containing protein; Belongs to the MCM family.	MCM6_C domain-containing protein.	0.997
A0A183PB98	A0A183PWM5	A0A183PB98	A0A183PWM5	MCM domain-containing protein; Belongs to the MCM family.	MCM domain-containing protein.	0.963
A0A183PB98	MCM7	A0A183PB98	A0A183NDT2	MCM domain-containing protein; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
A0A183PB98	SMTD_LOCUS210	A0A183PB98	A0A183NDM4	MCM domain-containing protein; Belongs to the MCM family.	MCM domain-containing protein; Belongs to the MCM family.	0.992
A0A183PB98	SMTD_LOCUS3062	A0A183PB98	A0A183NLS6	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.997
A0A183PB98	SMTD_LOCUS5919	A0A183PB98	A0A183NUY3	MCM domain-containing protein; Belongs to the MCM family.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.997
A0A183PB98	SMTD_LOCUS7887	A0A183PB98	A0A183P0K1	MCM domain-containing protein; Belongs to the MCM family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.998
A0A183PB98	SMTD_LOCUS9260	A0A183PB98	A0A183P4H4	MCM domain-containing protein; Belongs to the MCM family.	Zf-primase domain-containing protein.	0.993
A0A183PD61	A0A183PB98	A0A183PD61	A0A183PB98	Uncharacterized protein.	MCM domain-containing protein; Belongs to the MCM family.	0.996
A0A183PD61	A0A183PK31	A0A183PD61	A0A183PK31	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.998
A0A183PD61	A0A183PWI4	A0A183PD61	A0A183PWI4	Uncharacterized protein.	MCM6_C domain-containing protein.	0.998
A0A183PD61	A0A183PWM5	A0A183PD61	A0A183PWM5	Uncharacterized protein.	MCM domain-containing protein.	0.996
A0A183PD61	MCM7	A0A183PD61	A0A183NDT2	Uncharacterized protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
A0A183PD61	SMTD_LOCUS210	A0A183PD61	A0A183NDM4	Uncharacterized protein.	MCM domain-containing protein; Belongs to the MCM family.	0.995
A0A183PD61	SMTD_LOCUS3062	A0A183PD61	A0A183NLS6	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A183PD61	SMTD_LOCUS5919	A0A183PD61	A0A183NUY3	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.975
A0A183PD61	SMTD_LOCUS7887	A0A183PD61	A0A183P0K1	Uncharacterized protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.996
A0A183PD61	SMTD_LOCUS9260	A0A183PD61	A0A183P4H4	Uncharacterized protein.	Zf-primase domain-containing protein.	0.999