node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | purC | JSE7799_03845 | JSE7799_00810 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.604 |
carA | purD | JSE7799_03845 | JSE7799_02105 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.814 |
carA | purF | JSE7799_03845 | JSE7799_03088 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.953 |
carA | purH | JSE7799_03845 | JSE7799_00341 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Bifunctional purine biosynthesis protein PurH. | 0.884 |
carA | purL | JSE7799_03845 | JSE7799_00820 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.726 |
carA | purM | JSE7799_03845 | JSE7799_02997 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.803 |
carA | purN | JSE7799_03845 | JSE7799_02998 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylglycinamide formyltransferase. | 0.453 |
carA | purQ | JSE7799_03845 | JSE7799_00806 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.922 |
gcvP | purC | JSE7799_02860 | JSE7799_00810 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.848 |
gcvP | purD | JSE7799_02860 | JSE7799_02105 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.973 |
gcvP | purF | JSE7799_02860 | JSE7799_03088 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.889 |
gcvP | purH | JSE7799_02860 | JSE7799_00341 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Bifunctional purine biosynthesis protein PurH. | 0.886 |
gcvP | purL | JSE7799_02860 | JSE7799_00820 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.825 |
gcvP | purM | JSE7799_02860 | JSE7799_02997 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.498 |
gcvP | purN | JSE7799_02860 | JSE7799_02998 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylglycinamide formyltransferase. | 0.469 |
gcvP | purQ | JSE7799_02860 | JSE7799_00806 | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.929 |
purC | carA | JSE7799_00810 | JSE7799_03845 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.604 |
purC | gcvP | JSE7799_00810 | JSE7799_02860 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.848 |
purC | purD | JSE7799_00810 | JSE7799_02105 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.991 |
purC | purF | JSE7799_00810 | JSE7799_03088 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.992 |