STRINGSTRING
JNB_01720 protein (Janibacter sp. HTCC2649) - STRING interaction network
"JNB_01720" - DNA topoisomerase in Janibacter sp. HTCC2649
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JNB_01720DNA topoisomerase (ATP-hydrolyzing) (715 aa)    
Predicted Functional Partners:
JNB_01750
DNA topoisomerase (ATP-hydrolyzing) (816 aa)
  0.998
gyrA
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (921 aa)
  0.997
JNB_13403
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (377 aa)
 
  0.895
JNB_12673
Uncharacterized protein (335 aa)
     
 
  0.835
JNB_03775
DNA polymerase (889 aa)
   
 
  0.832
smc
Chromosome partition protein Smc ; Required for chromosome condensation and partitioning (1188 aa)
     
 
  0.814
dnaJ
Chaperone protein DnaJ ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (376 aa)
 
 
  0.812
dnaK
Heat shock protein 70 ; Acts as a chaperone (636 aa)
   
   
  0.793
JNB_07399
DNA helicase (729 aa)
   
 
  0.760
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (529 aa)
   
   
  0.744
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649
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