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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JNB_02685Putative phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase. (205 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
 
    0.894
JNB_20193
Phosphoribosyltransferase; COG0778 Nitroreductase.
  
 
 0.758
JNB_20518
Putative phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.
  
     0.744
JNB_03230
Putative phosphoserine phosphatase; COG3830 ACT domain-containing protein.
    
 0.696
JNB_17243
Putative cystathionine beta-synthase; COG0031 Cysteine synthase.
   
  0.683
JNB_19298
Probable D-3-phosphoglycerate dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.671
JNB_20213
Conserved protein, phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.
  
     0.665
JNB_02695
COG1765 Predicted redox protein, regulator of disulfide bond formation.
       0.633
JNB_05210
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
  0.626
JNB_02690
COG3797 Uncharacterized protein conserved in bacteria.
       0.582
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649
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