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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JNB_06359COG1587 Uroporphyrinogen-III synthase. (362 aa)    
Predicted Functional Partners:
JNB_06354
Putative uroporphyrin-III methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
 
 
 0.990
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.986
JNB_01890
uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
 
 
 0.972
JNB_06389
Hypothetical protein; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
  
 
 0.967
JNB_06344
Putative nitrite reductase (NAD(P)H) subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.919
JNB_09279
Putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase.
 
 
 0.914
JNB_09274
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 0.912
JNB_06349
COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
 
    0.903
JNB_14493
Hypothetical protein.
 
 
 0.899
hemE
Putative uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.870
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649
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