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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JNB_07424COG0210 Superfamily I DNA and RNA helicases. (1047 aa)    
Predicted Functional Partners:
JNB_07399
COG0210 Superfamily I DNA and RNA helicases.
 
 0.997
JNB_07419
COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily.
 
 
  0.973
JNB_01505
Hypothetical protein; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
  
 
 0.909
JNB_05994
COG0514 Superfamily II DNA helicase.
  
 0.890
JNB_13403
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.850
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.817
radA
Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.815
JNB_00995
Transfer protein Tra-like; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
  
 
 0.803
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.771
JNB_07429
COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
     
 0.758
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649
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