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disA protein (Janibacter sp. HTCC2649) - STRING interaction network
"disA" - Diadenylate cyclase in Janibacter sp. HTCC2649
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
disADiadenylate cyclase ; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process (360 aa)    
Predicted Functional Partners:
JNB_13643
Putative adenine glycosylase (304 aa)
              0.825
JNB_13648
Putative integral membrane protein (516 aa)
              0.805
JNB_13633
DNA repair protein radA ; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (463 aa)
   
   
  0.736
JNB_10389
Uncharacterized protein (97 aa)
   
          0.700
JNB_16399
Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ; Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (159 aa)
 
        0.498
JNB_19573
Uncharacterized protein (183 aa)
   
          0.454
JNB_02650
Uncharacterized protein (232 aa)
   
          0.440
JNB_16429
Putative tRNA/rRNA methyltransferase (316 aa)
              0.420
JNB_16424
Cysteinyl-tRNA synthetase (465 aa)
              0.420
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (164 aa)
              0.420
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649
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