disA protein (Janibacter sp. HTCC2649) - STRING interaction network

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disA

Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (360 aa)

Predicted Functional Partners:

radA

0.961

JNB_13643

0.796

JNB_13648

0.733

JNB_07424

0.684

JNB_10389

0.634

JNB_18093

0.454

JNB_16399

0.441

JNB_02630

0.424

JNB_13228

0.410

JNB_19843

0.410

Your Current Organism:

Janibacter sp. HTCC2649

NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
JNB_02630	JNB_10389	JNB_02630	JNB_10389	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	Hypothetical protein.	0.456
JNB_02630	JNB_13228	JNB_02630	JNB_13228	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	COG3879 Uncharacterized protein conserved in bacteria.	0.864
JNB_02630	JNB_18093	JNB_02630	JNB_18093	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	Putative secreted protein; COG1514 2'-5' RNA ligase.	0.485
JNB_02630	disA	JNB_02630	JNB_13638	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.424
JNB_07424	disA	JNB_07424	JNB_13638	COG0210 Superfamily I DNA and RNA helicases.	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.684
JNB_07424	radA	JNB_07424	JNB_13633	COG0210 Superfamily I DNA and RNA helicases.	Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.815
JNB_10389	JNB_02630	JNB_10389	JNB_02630	Hypothetical protein.	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	0.456
JNB_10389	JNB_13228	JNB_10389	JNB_13228	Hypothetical protein.	COG3879 Uncharacterized protein conserved in bacteria.	0.519
JNB_10389	JNB_18093	JNB_10389	JNB_18093	Hypothetical protein.	Putative secreted protein; COG1514 2'-5' RNA ligase.	0.627
JNB_10389	disA	JNB_10389	JNB_13638	Hypothetical protein.	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.634
JNB_13228	JNB_02630	JNB_13228	JNB_02630	COG3879 Uncharacterized protein conserved in bacteria.	Putative membrane protein; COG3856 Uncharacterized conserved protein (small basic protein).	0.864
JNB_13228	JNB_10389	JNB_13228	JNB_10389	COG3879 Uncharacterized protein conserved in bacteria.	Hypothetical protein.	0.519
JNB_13228	JNB_18093	JNB_13228	JNB_18093	COG3879 Uncharacterized protein conserved in bacteria.	Putative secreted protein; COG1514 2'-5' RNA ligase.	0.473
JNB_13228	disA	JNB_13228	JNB_13638	COG3879 Uncharacterized protein conserved in bacteria.	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.410
JNB_13643	JNB_13648	JNB_13643	JNB_13648	Putative adenine glycosylase; COG1194 A/G-specific DNA glycosylase.	Putative integral membrane protein.	0.782
JNB_13643	disA	JNB_13643	JNB_13638	Putative adenine glycosylase; COG1194 A/G-specific DNA glycosylase.	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.796
JNB_13643	radA	JNB_13643	JNB_13633	Putative adenine glycosylase; COG1194 A/G-specific DNA glycosylase.	Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.704
JNB_13648	JNB_13643	JNB_13648	JNB_13643	Putative integral membrane protein.	Putative adenine glycosylase; COG1194 A/G-specific DNA glycosylase.	0.782
JNB_13648	disA	JNB_13648	JNB_13638	Putative integral membrane protein.	Putative DNA-binding protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.	0.733
JNB_13648	radA	JNB_13648	JNB_13633	Putative integral membrane protein.	Putative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.465

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