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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JNB_14733COG0789 Predicted transcriptional regulators. (141 aa)    
Predicted Functional Partners:
JNB_17823
AccD3; COG0777 Acetyl-CoA carboxylase beta subunit.
   
  0.801
JNB_14738
COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.741
JNB_14743
Hypothetical protein; COG4120 ABC-type uncharacterized transport system, permease component.
       0.741
JNB_14748
Hypothetical protein.
       0.741
JNB_03815
Putative glutamate synthase (NADPH) large subunit; COG0067 Glutamate synthase domain 1.
    
  0.702
JNB_14728
COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
      0.675
dnaJ
Putative DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dn [...]
  
   0.556
JNB_15383
COG2214 DnaJ-class molecular chaperone.
  
   0.556
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.518
icmF
methylmalonyl-CoA mutase, N-terminal; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.498
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649
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