EAQ40545.1 protein (Dokdonia sp. MED134) - STRING interaction network

Nodes:

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second shell of interactors

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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

EAQ40545.1

Predicted membrane protein. (115 aa)

Predicted Functional Partners:

EAQ40546.1

0.786

EAQ40544.1

0.677

Your Current Organism:

Dokdonia sp. MED134

NCBI taxonomy Id: 313590
Other names: Cellulophaga sp. MED134, D. sp. MED134, Dokdonia donghaensis MED134

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAQ40544.1	EAQ40545.1	MED134_07304	MED134_07309	dTDP-4-dehydrorhamnose reductase.	Predicted membrane protein.	0.677
EAQ40544.1	EAQ40546.1	MED134_07304	MED134_07314	dTDP-4-dehydrorhamnose reductase.	2OG-Fe(II) oxygenase superfamily protein; Alkylated DNA repair protein.	0.603
EAQ40545.1	EAQ40544.1	MED134_07309	MED134_07304	Predicted membrane protein.	dTDP-4-dehydrorhamnose reductase.	0.677
EAQ40545.1	EAQ40546.1	MED134_07309	MED134_07314	Predicted membrane protein.	2OG-Fe(II) oxygenase superfamily protein; Alkylated DNA repair protein.	0.786
EAQ40546.1	EAQ40544.1	MED134_07314	MED134_07304	2OG-Fe(II) oxygenase superfamily protein; Alkylated DNA repair protein.	dTDP-4-dehydrorhamnose reductase.	0.603
EAQ40546.1	EAQ40545.1	MED134_07314	MED134_07309	2OG-Fe(II) oxygenase superfamily protein; Alkylated DNA repair protein.	Predicted membrane protein.	0.786

Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.847

expected number of edges:

12

PPI enrichment p-value:

7.35e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051205

Protein insertion into membrane

6 of 8

2.21

3.94

5.90e-09

GO:0071709

Membrane assembly

6 of 12

2.04

3.5

1.81e-08

GO:0043163

Cell envelope organization

6 of 12

2.04

3.5

1.81e-08

GO:0043165

Gram-negative-bacterium-type cell outer membrane assembly

5 of 11

1.99

2.95

3.77e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009279

Cell outer membrane

6 of 55

1.37

1.64

1.16e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1388

Protein insertion into membrane

5 of 5

2.34

3.55

9.24e-08

CL:3083

Mixed, incl. AsmA-like, C-terminal, and STAS domain

3 of 6

2.04

1.66

0.00054

CL:3047

Mostly uncharacterized, incl. AsmA-like, C-terminal, and Peptidoglycan binding

4 of 40

1.34

1.08

0.0019

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009279

Cell outer membrane

6 of 40

1.51

1.96

3.83e-06

GOCC:0071944

Cell periphery

7 of 347

0.64

0.45

0.0099

GOCC:0016020

Membrane

8 of 434

0.6

0.44

0.0051

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0998

Cell outer membrane

4 of 30

1.46

1.14

0.0022

KW-0449

Lipoprotein

3 of 18

1.56

0.95

0.0098

KW-0732

Signal

5 of 164

0.82

0.47

0.0381

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