Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EAR11809.1Hypothetical protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (286 aa)    
Predicted Functional Partners:
ftsH
Putative transmembrane AAA-metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.677
EAR11807.1
Hypothetical protein; COG1577 Mevalonate kinase.
 
     0.520
EAR11808.1
COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
       0.514
EAR13944.1
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.485
EAR11765.1
Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR13689.1
Putative metallopeptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR13690.1
Probable peptidase; COG0612 Predicted Zn-dependent peptidases.
   
  0.461
EAR12447.1
COG4877 Uncharacterized protein conserved in bacteria.
  
    0.455
EAR11806.1
Fumarate reductase/succinate dehydrogenase flavoprotein-like; COG2081 Predicted flavoproteins.
       0.449
EAR12849.1
Zinc-containing alcohol dehydrogenase superfamily protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
 
 
  0.446
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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