Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EAR13115.1COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. (208 aa)    
Predicted Functional Partners:
thrA
Bifunctional aspartokinase I/homoserine dehydrogenase I; COG2021 Homoserine acetyltransferase.
  
 0.947
EAR13079.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
    
  0.907
EAR13918.1
Putative aspartokinase I-homoserine dehydrogenase; COG0527 Aspartokinases.
  
 0.875
EAR13249.1
COG2873 O-acetylhomoserine sulfhydrylase.
  
 
 0.845
trpF
COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
   
 
 0.734
EAR12023.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
    
  0.728
EAR11723.1
Rotamase; COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1.
  
 
  0.663
EAR12929.1
COG0460 Homoserine dehydrogenase.
 
 0.649
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.633
EAR13437.1
COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
 
 
  0.628
Your Current Organism:
Polaribacter irgensii
NCBI taxonomy Id: 313594
Other names: P. irgensii 23-P, Polaribacter irgensii 23-P
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